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Mentor Signs Agreement with Niadyne for Distribution of Science-Based Skin Restoration Cosmeceutical Products

(press release from Mentor Corporation)

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SANTA BARBARA, Calif. & RESEARCH TRIANGLE PARK, N.C.--March 20, 2006--Mentor Corporation (NYSE:MNT), a leading supplier of medical products in the United States and internationally, today announced that it had signed a distribution agreement with Niadyne Inc., a privately-owned company dedicated to the discovery and development of uniquely efficacious topical products, to distribute Niadyne's innovative NIA 24(TM) line of science-based cosmeceutical products used to improve and restore the healthy appearance of the skin. Terms of the agreement were not disclosed.

"The NIA 24 family of products provides an innovative, simple, yet scientific solution that allows patients to restore and improve the healthy appearance of their skin," commented Joshua H. Levine, President and Chief Executive Officer of Mentor Corporation. "We believe that these cosmeceutical products will complement our future dermal filler and botulinum toxin products and are pleased to partner with Niadyne as we continue to expand our range of science-based, aesthetic-medicine products."

Cosmeceuticals are topical products that contain an active ingredient designed to enhance the healthy appearance of the skin diminishing the appearance of wrinkling, aging and skin discoloration. The U.S. market for cosmeceutical products is estimated by the Freedonia Group to reach approximately $5 billion in 2007.

"We are delighted to join with Mentor for the distribution of NIA 24 Niacin-Powered Skin Therapy," said Melisse Shaban, Chief Executive Officer of Niadyne, Inc. "The reach and professionalism of Mentor's sales team are unparalleled in the industry. With Mentor's support, we will be able to provide even more physicians, and their patients, with Niadyne's breakthrough skin care products."

NIA 24 Niacin-Powered Skin Therapy is based on Pro-Niacin(TM), a proprietary, patented niacin derivative that allows niacin to be delivered to skin at optimal rates allowing conversion to its active form, nicotinamide adenine dinucleotide or NAD. Twenty-five years of published research has shown that NAD helps protect against the damage caused to the skin by sun exposure, aging and other environmental factors. These products will only be available to patients through physicians and physician directed medi-spas.

About Mentor Corporation

Founded in 1969, Mentor Corporation is a leading supplier of medical products for the global healthcare market. The Company develops, manufactures and markets innovative, science-based products for the aesthetics, urologic specialties and clinical and consumer healthcare markets around the world. The Company's website is www.mentorcorp.com.

About Niadyne, Inc.

Niadyne, Inc., was founded in 1997 by the company's principal scientists, Elaine Jacobson, Ph.D., and Myron Jacobson, Ph.D., who are professors at the University of Arizona College of Pharmacy and members of the Arizona Cancer Center. Niadyne, Inc. is involved in the discovery of uniquely efficacious molecules that penetrate the skin to address unmet healthcare needs. Product development is focused on the treatment and prevention of sun damage to skin, optimization of scalp and hair follicle function and optimization of cholesterol and other blood lipids. The company created NIA 24(TM) Niacin-Powered Skin Therapy, based on more than 25 years of biomedical research. To learn more about the products, visit www.nia24.com

Safe Harbor Statement

All statements included or incorporated by reference in this release, other than statements or characterizations of historical fact, are forward-looking statements. These forward-looking statements are based on our current expectations, estimates and projections about our industry, management's beliefs and certain assumptions made by us. Forward-looking statements in this press release include but are not limited to those statements related to our belief that these cosmeceutical products will complement our future dermal filler and botulinum toxin products, our continued expansion of our range of science-based, aesthetic-medicine products, the Freedonia Group's estimate that the U.S. market for cosmeceutical products is expected to reach approximately $5 billion in 2007, our support in enabling Niadyne, Inc. to provide even more physicians, and their patients, with Niadyne's breakthrough skin care products, and the expectation that the products described in this release will only be available to patients through physicians and physician directed medi-spas. Forward-looking statements can also be identified by words such as "anticipates," "expects," "intends," "plans," "predicts," "believes," "seeks," "estimates," "may," "will," "should," "would," "could," "provide," "potential," "continue," similar expressions, and variations or negatives of these words. In addition, any statements that refer to expectations, projections or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking statements.

These forward-looking statements speak only as of the date hereof and are based upon the information available to us at this time. Such information is subject to change, and we will not necessarily inform you of such changes. These statements are not guarantees of future results and are subject to risks, uncertainties and assumptions that are difficult to predict. Therefore, our actual results could differ materially and adversely from those expressed in any forward-looking statement as a result of various factors.

The Securities and Exchange Commission filings of Mentor, including, without limitation, its Annual Reports on Form 10-K, subsequent quarterly reports on Form 10-Q, and recent Current reports on Form 8-K, discuss important risk factors that could contribute to such differences or otherwise affect its business, results of operations and financial condition. Mentor undertakes no obligation to revise or update publicly any forward-looking statement for any reason.

Mentor Corporation
Peter R. Nicholson, 805-879-6082
or
Niadyne, Inc.
Giulia Arencibia, 212-757-6880


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